Sleep Challenges During Midlife: The Critical Role of Rest
Anna Harrelson • June 2, 2024

Restoring Rest: Navigating Sleep Challenges in Menopause with Research-Based Insights and Practical Tips

Described as the Swiss Army knife of health, sleep is crucial for everyone, but its importance is magnified during menopause. If we're not getting enough rest, our bodies miss out on essential recovery processes such as brain detoxification, nervous system balance, and efficient metabolism. Let’s delve deeper into the sleep challenges of menopause, including insights from leading experts and relevant studies.


Hormonal Changes and Their Impact on Sleep

The menopause transition brings significant fluctuations in hormones such as estrogen and progesterone, which profoundly impact sleep. Estrogen helps regulate neurotransmitter systems that influence our sleep cycles. As estrogen levels decline, so does our ability to fall and stay asleep. Progesterone, known for its calming effects, also diminishes, leading to lighter and more disrupted sleep.


Lisa Mosconi, PhD, in her book The Menopause Brain, discusses specific brain changes during menopause linked to sleep disruption. She references studies that show reduced glucose metabolism in the brain during menopause, which not only affects cognitive functions but also sleep quality. Dr. Mosconi advocates for a holistic approach to managing these changes, emphasizing proper nutrition and hydration as keys to supporting brain health and sleep.


Matthew Walker, PhD, a renowned sleep researcher, highlights in his book Why We Sleep the importance of deep sleep in clearing beta-amyloid, a toxic protein linked to Alzheimer’s Disease. His research demonstrates that poor sleep quality can lead to an accumulation of these proteins, particularly troubling for menopausal women who are already at a higher risk due to hormonal changes.


Practical Tips for Better Sleep Hygiene

To combat these challenges, adopting effective sleep hygiene practices is essential. Here are strategies supported by research:

  1. Consistent Sleep-Wake Schedule: Studies show that a regular sleep schedule helps to stabilize your circadian rhythms, improving overall sleep quality.
  2. Optimal Sleep Environment: Research supports maintaining a bedroom environment conducive to sleep—cool, quiet, and dark. Consider using adaptive bedding materials suitable for temperature fluctuations common in menopause.
  3. Mindful Eating and Drinking: Avoid caffeine and alcohol close to bedtime, as they can alter sleep architecture, reducing the proportion of deep sleep.  I suggest stopping all calorie intake at least 2 hours prior to bedtime.
  4. Wind-Down Routine: Engaging in relaxing activities before bed can enhance sleep quality. Activities like reading or meditation support brain health and prepare the mind for rest.
  5. Screen Time Reduction: Research points out that the blue light from screens inhibits melatonin production, disrupting sleep. Using devices with night modes or avoiding screens an hour before bed can be beneficial.
  6. Consideration of Natural Sleep Aids: Some studies suggest that supplements like melatonin and valerian root can help improve sleep during menopause, though it’s crucial to consult with a healthcare provider before starting any new supplement.


Exploring Hormonal Treatments

For those experiencing severe disruptions and other bothersome symptoms of the menopause transition, Menopause Hormone Therapy (MHT) may be an option. MHT can help stabilize mood and improve sleep patterns by replenishing estrogen and progesterone levels.

Understanding and addressing sleep issues during menopause is crucial for maintaining overall health. By integrating insights from experts and applying practical sleep hygiene tips, we can navigate this transition more smoothly and ensure that our bodies and brains receive the rest they need.


I encourage you to explore these strategies and share your experiences. Together, we can support each other and improve our sleep and overall well-being during menopause.


Warm regards,

Dr. Anna


WonderCreek Health Blog

By Anna Harrelson June 13, 2025
You’ve probably seen it popping up in wellness podcasts, health stores, or even your friend's supplement cabinet: bovine colostrum. Marketed for gut health, immune support, and recovery, this early-life nutrient source for calves is now showing up in adult wellness routines. But is it worth your time and money? As a lifestyle medicine physician focused on women’s midlife health and longevity, here’s what I want you to know before you jump on the colostrum bandwagon. Let’s Start With the Basics: What Is Colostrum? Colostrum is the first form of milk produced by mammals (including humans) in the first few days after giving birth. It’s loaded with antibodies, growth factors, and immune-modulating compounds designed to jumpstart a newborn’s immune system and line the gut. Bovine colostrum—from cows—is the form used in most supplements. It's freeze-dried and packaged into powders or capsules, and often promoted for: Gut barrier support ("leaky gut") Immune system priming Exercise recovery Anti-aging benefits But let’s be honest: just because something has growth factors doesn’t mean it belongs in your Amazon cart. Does the Science Support It? Evidence in humans is limited— but not nonexistent. Some small clinical studies have shown potential benefits: Gut health: In people with NSAID-induced intestinal permeability ("leaky gut"), bovine colostrum has been shown to reduce damage and symptoms. Immune function: Some data in athletes suggests reduced upper respiratory infections. Exercise recovery: A few studies report improvements in performance, gut comfort, or muscle soreness—especially in endurance athletes. But these benefits aren’t guaranteed. And the quality and dosage of colostrum varies widely, with no standardized formulation across brands. So Should You Take It? Here’s where my clinical voice kicks in: Before you reach for colostrum, ask yourself: Have you addressed the basics? Are you sleeping? Managing stress? Eating fiber and whole foods? Getting enough protein? Building muscle? Moving your body? Supporting your gut with real food (not just powders)? If the answer is no—then colostrum is not your next step. You’re throwing powdered fuel on an engine that’s missing spark plugs. Do you have dairy sensitivity? Colostrum is a dairy product. Even if it's low in lactose, it may not be tolerated by everyone. Are you already taking quality foundational supplements? Vitamin D, omega-3s, magnesium, creatine, iron (when needed), and probiotics have stronger bodies of evidence for many women in midlife. When Might It Be Worth Trying? Colostrum might be a reasonable add-on if you: Have mild gut symptoms (especially post-infectious or stress-related) Are recovering from illness or antibiotics Train hard and experience frequent upper respiratory issues Want to support your immune system during travel or stress Even then, I recommend: A 2–3 month trial only after dialing in basics Choosing a third-party tested brand Tracking symptoms and benefits Cost, Hype, and the Bigger Picture Many women I work with are overwhelmed by supplement costs. Colostrum can run $50–100/month —and that adds up. So here’s what I tell my patients: Just because something is trending doesn’t mean it’s essential. And just because it works for someone on TikTok doesn’t mean it’s the right tool for your body right now. Your body is an incredible machine. When you give it rest, movement, nourishment, and support—it can do amazing things. Colostrum is not magic. It’s just one tool in a very big toolbox. Bottom Line Colostrum may hality sources. You’re not broken. You might just need a reset—not another powder.
By Anna Harrelson June 12, 2025
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